Megalochori is the capital of Agistri and the biggest settlement of the island with 561 inhabitands. Megalochori, also known as "Mylos", is situated to the west of Skala and is the Administrative capital of the island. The community's headquarters are situated in Megalochori.

It has a natural port and a refueling marina for boats. Furthermore, this is the docking area for Flying Dolphins arriving from Piraeus.

Emerald crystal clear waters among natural bays which create sandy areas.

Picturesque stone-paved alleys, traditional houses, cafeterias, elderly figures with local garments and the unique wind-mill, present through their existence this land's vivid history.

At Megalochori someone can admire the Church os Zoodochos Pigi, at the center of the village (1885). Stone made houses, white-washed benches, indian-red roofs, home-made bakeries, tidy yards meet the modern hotel units.  Taverns, restaurants, cafes, snack-bars and clubs are eager to host in the best way all of you who visit our island.

Leaving the village and towards the pine-dwelled woods the visitor meets the small church of Saint Apostolon, an old church which invites the visitor to learn about the island's roots, Kadoudi, meaning the old village, what is left of Agistri's oldest settlement.